Seroxat

Drug name: Generic Paroxetine

Active Ingredients:

• Paroxetine

Other names used:

• Parotin®
• Paxil®
• Pexeva®

Therapeutic actions:

Generic paroxetine is a selective inhibitor of serotonin reuptake. By inhibiting the reuptake paroxetine increases blood levels of serotonin in the synaptic gap and improves the cooperation of brain cells (neurons). This is considered beneficial for the relief of depression symptoms. The medication possesses a low affinity to m-choline receptors, 1-, 2- and -adrenoreceptors, D2-dopamine receptors. The medication does not affect blood pressure, heart rate and ECG.

Indications:

• Obsessive-compulsive disorder (OCD)
• Panic disorder
• Depression (also known as major depression or clinical depression)
• Social anxiety disorder
• Generalized anxiety disorder (GAD)
• Post-traumatic stress disorder (PTSD).

Contraindications and cautions:

• Hypersensitivity to any of the medications ingredients
• Simultaneous use of MAO inhibiting and a period of 14 days after their use
• Unstable epilepsy
• Children and adolescents under 18 years of age
• Manic episodes of bipolar affective disorder (manic depression)
• Pregnancy
• Breastfeeding

The medication should be used with caution in: renal failure, hepatic failure, closed-angle glaucoma, diabetes, hyperplasia of the prostate gland, mania, heart problems, epilepsy, seizures, simultaneous indication of countershock therapy, simultaneous indication of medicines which increase the risk of bleedings.

Adverse effects: There are possible side-effects associated with this medicine that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using Paroxetine will experience it or any other. Paroxetine may cause the following side effects:

• CNS and peripheral system: drowsiness, tremor, asthenia, insomnia, dizziness, fatigability, seizures, extrapyramidal disorders, serotonin syndrome, hallucinations, mania, confusion, agitation,nervousness, panic attacks, amnesia, depersonalizations.
• Sense organs:vision disorders
• Locomotor system: arthralgia, myalgia, muscle weakness, miopathy.
• Urogenital system: urine retention,
• Sexual function: sexual dysfunction, ejaculation problems, anorgasmia, galactorrhea
• Digestive system: decreased or increased appetite, taste changes, nausea, constipation, diarrhea, hepatitis
• Cardiovascular system: low blood pressure
• Allergic reactions: skin rash, hives, itching, edema
• Other: increased sweating, rhinitis, low sodium blood levels ADH secretion problems

The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

For more information about any other possible risks associated with Paroxetine, please read the information provided with Paroxetine or consult your doctor or pharmacist.

Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with Paroxetine. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe. Paroxetine may interact with the following medicines:

• Alcohol
• NSAID's including and aspirin
• MAO inhibitors
• Blood thinners
• Tryptophan
• Anti-arrhythmia medications
• Seizures preparations
• Cardiac glycosides
• H2 histamine receptor blockers
• ADHD treatment
• Phenothiazine medications
• Antipsychotics
• Parkinon's disease treatment
• Bipolar disorders treatment
• Other SSRI or SNRI medications
• Tricyclic antidepressants
• Xantines
• Triptans
• Narcotic pain killers (tramadol)
• Cancer medications ( tamoxifen)
• St. John's wort

Additional Information: DO NOT SHARE Paroxetine with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.

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