Zoloft
Other names used:
- Lustral®
Active Ingredients:
sertraline hydrochloride
Therapeutic actions: Acts as an Antidepressant by inhibiting CNS neuronal uptake of serotonin; blocks uptake of serotonin with little effect on norepinephrine, muscarinic, histaminergic, and alpha1-adrenergic or dopaminergic receptors.
Indications:
- Treatment of major depressive disorder
- Treatment of obsessive-compulsive disorders (OCD)
- Treatment of panic disorder with or without agoraphobia
- Treatment of posttraumatic stress disorder; long-term use to prevent relapse and sustain symptom improvement
- Treatment of premenstrual dysphoric disorder (PMDD)
- Unlabeled use: generalized social phobia
Contraindications and cautions:
- Contraindicated with hypersensitivity to sertraline; pregnancy.
- Use cautiously with impaired hepatic or renal function, lactation.
Adverse effects: Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
- CNS: Headache, nervousness, drowsiness, anxiety, tremor, dizziness, insomnia, light-headedness, agitation, sedation, abnormal gait, convulsions, vision changes, fatigue
- CV: Hot flashes, palpitations, chest pain
- Dermatologic: Sweating, rash, pruritus, acne, contact dermatitis
- GI: Nausea, vomiting, diarrhea, dry mouth, anorexia, dyspepsia, constipation, taste changes, flatulence, gastroenteritis, dysphagia, gingivitis
- GU: Painful menstruation, sexual dysfunction, frequency, cystitis, impotence, urgency, vaginitis
- Respiratory: Upper respiratory infections, pharyngitis, cough, dyspnea, bronchitis, rhinitis
- Other: Hot flashes, fever, back pain, thirst
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
- Serious, sometimes fatal, reactions with MAO inhibitors; allow at least 14 days to elapse between MAOI and sertraline use
- Increased serum levels of sertraline with cimetidine
- Possible risk of increased QTc interval if combined with pimozide; do not use together - Drug-food
- Increased rate of absorption with food
Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.
