Duotrol
Drug name: Duotrol
Other names used:
- Benclamet®
- Benclamet forte®
- glibonet®
- glibonet forte®
- gluconil-M®
- Glucovance®
Active Ingredients:
- Glibenclamide,
- Metformine
Therapeutic actions: Glyburide and metformin both are oral diabetes medicine. They are used to control the sugar levels in the blood. Mixture of this drugs have proved to be more potent then the drugs alone.
Indications: Duotrol is used to treat uncontrolled non insulin dependent diabetes which is not responding to biguadine and sulphonylureas therapy. Duotrol in other words is used for people with diabetes type 2.
Contraindications and cautions: If you are taking Duotrol (glyburide and metformine) a life threatening condition called lactic-acidosis can develop. You should get immediate help if any of the following symptoms start to manifest: Increasing sleepiness, cold feeling, weakness, slow heart rate, muscle pain, shortness of breath, stomach pain, lightheadedness or fainting.
If you suffer form congestive heart failure, kideny disease, liver disease, or you are in a state of diabetic ketocaidosis be sure to consult your local health care professional before using Duotrol and may need a dosage adjustment.
Duotrol is in the pregnancy category B. Consult your doctor regarding the use of Duotrol if you are pregnant, planning to become pregnant or breastfeeding a baby.
All the information regarding individual risk of Duotrol usage can be acquired at your local health care professinal.
Adverse effects: There are possible side-effects associated with this medicine that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using Duotrol will experience it or any other.
Stop using Duotrol and call your doctor as son as possible if any of the following symptoms start to manifest: Hives, difficulty breathing, swelling, short breath or mild exertion, rapid weight gain. Other less serious side effects are:
- Headache
- sneezing, cough, signs of a cold
- mild nausea, vomiting, stomach pain , diarrhea
- dizziness
The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with Duotrol, please read the information provided with this drug or consult your doctor or pharmacist.
Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with Duotrol. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe.
Be sure not to mix glyburide and metformin with other drugs which raise or lower your blood sugar because of the possibility to increase their effectiveness. Interactions with duotrol have been shown by the following medicine:
- morphine
- ciprofloxacin
- furosemide
- quinidine
- trimethoprim
- cimetidine or ranitidine
- nifedipine
- vancomycin
- amiloride or triamterene
- procainamide
- digoxin
If any of this drugs are used by you then you may need a dosage adjustment or special monitoring during treatment.
Additional Information: DO NOT SHARE DUOTROL with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.

