Cordaflex
Drug name: Cordaflex
Active Ingredients:
- Nifedipine
Therapeutic actions: The active ingredient of Nifedipine belongs to a group of medicines called calcium channels blockers. Nifedipine works by blocking a certain number of calcium channels that are found in the walls of the blood vessels. Calcium ions enter the muscle cells of the vessels and cause them to constrict. By blocking calcium channels, Nifedipine decreases the number of calcium inside the cells, resulting in relaxing of muscle cells and reducing high blood pressure inside the blood vessels. Nifedipine reduces the spasm and dilates coronary and peripheral arterial vessels, decreases total peripheral resistance, afterload and heart requirement in oxygen. Nifedipine doesn't act on atrioventricular node and doesn't exert antiarrhythmic action.
Indications: Cordaflex is used to treat the following cardiovascular diseases:
- Hypertension
- Coronary heart disease(rapid relief of symptoms related to angina)
Cordaflex can also be recommended to treat Raynaud's syndrome
Contraindications and cautions: You should not tale Nifedipine if you experience the following conditions:
- Allergy or hypersensitivity to Nifedipine or other calcium blockers
- Stenocardia(angina) that is not controlled by the drug therapy
- Aortic stenosis
- Heart failure(cardiogenic shock)
- Patients who experienced a heart attack in the last mouth
- Blood disease called porphyrias.
- In children
Talk with your health care provider prior to taking Nifedipine in:
- Elderly age
- Liver failure
- People having kidney dialysis.
- left ventricular dysfunction
- Hypotension.
- Diabetes.
Warning!
Do not drink grape fruit juice while taking Nifedipine.
Nifedipine is not used to treat an attack of angina.
At the beginning of treatment with Cordaflex is not recommended to drive or operate any machinery.
Adverse effects: There are possible side-effects associated with this medicine that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using Cordaflex will experience it or any other.
- CNS: Headache, dizziness, tiredness, flushing, tiredness, depression, myalgia, paraesthesia, tremor
- Digestive system: diarrhea, constipation, nausea, vomiting, indigestion or abdominal pain.
- Cardiovascular system: heart palpitations, tachycardia
- Allergic reactions: skin rash and itching
- Others: peripheral oedema, impotence, gynaecomastia, gingival hyperplasia
The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with Cordaflex, please read the information provided with Cordaflex or consult your doctor or pharmacist.
Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with Cordaflex. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe.
Nifedipine may interact with the following medications:
- ACE inhibitors
- Alpha-blockers such as prazosin
- Angiotensin II receptor antagonists
- Beta-blockers
- Calcium-channel blockers
- Clonidine
- Nitrates
- Antidepressants
- Antipsychotic medications
- Alprostadil
- Baclofen
- Benzodiazepines
Cimetidine, Fluconasole, Foluoxetine and itraconazole may increase the blood levels of Nifedipine
Carbamazepine, phenytoin and phenobarbital decreases the blood levels of Nifedipine
Cordaflex may increase blood levels of the following medicines:
- phenytoin
- digoxin
- tacrolimus
- theophylline.
Additional Information: DO NOT SHARE Cordaflex with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.
