Avonex
Drug name: Avonex
Other names used:
- Rebif®
Active Ingredients:
Interferon beta-1a
Therapeutic actions: Interferon beta-1a is a protein. Interferons are released in the body in response to viral infections. Interferons are important for fighting viruses in the body, regulating reproduction of cells, and regulating the immune system.
Indications: Interferon beta-1a is a specific interferon used in the treatment of relapsing multiple sclerosis to slow the development of physical disability and to decrease the frequency of exacerbations.
Contraindications and cautions: Before using this medication, tell your doctor if you currently have or have had in the past
- depression, suicidal thoughts, or anxiety;
- epilepsy or another seizure disorder;
- liver disease;
- alcohol abuse;
- thyroid problems;
- blood problems such as easy bruising or bleeding, anemia (low red blood cells), or low white blood cells;
- angina;
- congestive heart failure; or
- irregular heartbeats.
You may not be able to use interferon beta-1a, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above.
Interferon beta-1a is in the FDA pregnancy category C. This means that it is not known whether interferon beta-1a will harm an unborn baby. Interferon beta-1a may cause a miscarriage or spontaneous abortion. Do not use this medication if you are pregnant or could become pregnant during treatment. It is not known whether interferon beta-1a passes into breast milk. Do not use this medication without first talking to your doctor if you are breast-feeding a baby.
Adverse effects: The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
If you experience any of the following serious side effects, stop using interferon beta-1a, and seek emergency medical attention or contact your doctor immediately:
- an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
- skin rash, itching, or bumps;
- depression, anxiety, or suicidal thoughts;
- seizures;
- yellowing of the skin or eyes; or
- unusual bruising or bleeding.
Flulike symptoms (fever, chills, sweating, muscle aches, tiredness) are likely to occur. They are most common at the start of therapy and may decrease with continued use. Over-the-counter medications for pain and fever may help to alleviate these symptoms. Discuss with your doctor the use of medication to reduce these side effects.
Other less serious side effects may be more likely to occur. Continue to use interferon beta-1a and notify your doctor if you experience
- headache;
- nausea, vomiting, or loss of appetite;
- weakness;
- dizziness or drowsiness; or
- redness, pain, bruising, or swelling at the injection site.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
Interactions: It is not known if other drugs interact with interferon beta-1a. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.
Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.
