Nimesil
Drug name: Nimesil
Other names used:
- Ainex®
- Aulin®
- Donulide®
- Drexel®
- Edrigyl®
- Eskaflam®
- Heugan®
- Mesulid®
- Minapon®
- Nexen®
- Nimed®
- Nimedex®
- Nimutab®
- Nisulid®
- Scaflam®
- Scaflan®
Active Ingredients:
Nimesulide
Therapeutic actions: Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties and a specific mode of action. Nimesulide acts by inhibiting the release of tumour necrosis factor-alpha, acts as a competitive inhibitor of histamine release and reduces superoxide anion formation.
Indications:
Nimesulide is indicated for the treatment of acute pain, the symptomatic treatment of painful osteoarthritis and primary dysmenorrhoea.
Contraindications and cautions:
- Known hypersensitivity to Nimesulide or to any of the excipients of the products.
- History of hypersensitivity reactions(bronchospasm, rhinitis, urticaria) in response to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs.
- History of hepatotoxic reactions to Nimesulide
- Active gastric or duodenal ulcer, a history of recurrent ulceration or gastrointestinal bleeding, cerebrovascular bleeding or other active bleeding or bleeding disorders.
- Severe coagulation disorders
- Severe heart failure
- Severe renal impairment
- Children under 12 years
- The third trimester of pregnancy and breastfeeding
Adverse effects: Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect. Diarrhoea
- Vomiting
- Skin rash
- Pruritis
- Dizziness
- Headache
Like most drugs in NSAID category, Nimesulide is known to be hepatotoxic (damaging to the liver) in rare but unpredictable cases and should be taken with care.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.
Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.
Especially pay attention to the following drugs:
- Warfarin (Coumadin®, Jantoven®)
- Other nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen (Advil®, Motrin®), naproxen (Aleve®, Anaprox®, Naprosyn®, Naprelan®), diclofenac (Cataflam®, Voltaren®), indomethacin (Indocin®), nabumetone (Relafen®), oxaprozin (Daypro®), celecoxib (Celebrex®), etodolac (Lodine®, Lodine® XL), and others
- Aspirin
- Lithium (Eskalith®, Lithane®, Lithonate®, Lithotabs®)
- Diuretics, such as torsemide (Demadex®), furosemide (Lasix®), and hydrochlorothiazide
- ACE inhibitors, such as lisinopril (Zestril®, Prinivil®), fosinopril (Monopril®), captopril (Capoten®), quinapril (Accupril®), benazepril (Lotensin®), enalapril (Vasotec®), or ramipril (Altace®)
- Methotrexate (Rheumatrex®, Trexall™)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Cholestyramine (Questran®, Questran® Light, Prevalite®, LoCholest®)
- Corticosteroids, such as prednisone, hydrocortisone (Cortef®), dexamethasone (Decadron®, Dexone®, Hexadrol®), and many others.
Several herbal and nutritional supplements can also interact with meloxicam and may increase the risk of bleeding. Examples of these include but are not limited to:
- Dong quai
- Feverfew
- Garlic
- Ginger
- Ginkgo biloba
- Ginseng
- St. John's wort
- Fish oil supplements.
Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.
