Spasmalgon
Drug name: Spasmalgon
Other names used:
- Algifen®
- Baralgin®
Active Ingredients:
Fenpiverinium bromide, Metamizole sodium, Pitofenone
Therapeutic actions: A combined drug with a potent spasmolytic and analgesic action. Its spasmolytic effect is due to direct myotropic action and M-cholinolytic action on the smooth muscles of the spastically contracted organs. Its analgesic effect is determined by the central and peripheral action of analgin included in the drug. Analgin, on the one hand, reduces inflammation and inhibits the formation of allogenic substances and, on the other, it stimulates the non-opiate antinociceptive system by inhibiting the synthesis of prostaglandins. Spasmalgon has a certain antipyretic and antiphlogistic action. It suppresses the respiratory center and is distinguished by its very quick and long-lasting effect. Injected intramuscularly, the effect occurs after 20-30 min, intravenously - after 2-3 min.
Indications: Painful spasms of smooth muscles - renal colic, spasms of the ureter, tenesmus of the urinary bladder, biliary colic, dyskinesia of the biliary ducts, intestinal and gastric colic, spastic dysmenorrhea, light and moderately severe paroxysms of bronchial asthma.
Contraindications and cautions: Hypersensitivity to any component of the preparation; hypersensitivity to acetylsalicylic acid or other non-steroidal anti-inflammatory drugs; blood dyscrasia; bone marrow suppression; active gastric or duodenal ulceration; sever hepatic or renal impairment; paralytic ileus; history of gastrointestinal ulcerations; acute intermittent porphyria; glucoso-6-phosphate deficiency; anaemia; hypertension; cardiac insufficiency; fluid retention; circulatory collapse tendency; prostatic hypertrophy; closed-angle glaucoma; mechanical causes of intestinal obstruction; megacolon; pregnancy, lactation. The preparation is not intended for children under 14 years of age.
Adverse effects: The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.
The main side effects are due to hypersensitivity to analgin, the most important being shock and changes in the blood count (agranulocytosis and thrombocytopenia). Dryness of the mouth, disturbed accommodation, urticarial rashes, skin and mucosa itching can be observed, as well as disorders of the renal functions, especially in predisposed patients.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.
Interactions: Tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine.
- In simultaneous treatment with H1-hystoblockators, butyrophenones, phenothiazines, tricyclic antidepressants, amantadine and quinidine is possible strengthening in M-anticholinergic activity
- Spasmolgon strengthens the effects of ethanol;
- simultaneous application with the chlorpromazine or other derivatives of phenothiazine can lead to the development of the expressed hyperthermy.
- Tricyclic antidepressants, oral contraceptives and allopurineol increase the toxicity of preparation.
- Phenylbutazone, barbiturates and other hepatoinductors in simultaneous designation decrease the effectiveness of metamizole sodium.
- Sedative and anxiolytic (tranquilizers) strengthen the analgesic action of metamizole sodium.
- X-ray contrast crude drugs, colloidal blood substitutes and penicillin must not be used during with spasmolgon.
- Simultaneous designation of Spsasmolgon with cyclosporines reduces the concentration of cyclosporines in blood.
- Tiamazol and cytostatics increase the risk of leucopenia development.
Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.
