Warfarex

Drug name: Warfarex

Active Ingredients:

warfarin

Therapeutic actions: Warfarex contains the active ingredient warfarin that belongs to indirect action anticoagulants(blood-thinners), Warfarex works by inhibiting the production of vitamin-K dependent blood-coagulation factors((II, VII, IX � X) and proteins C and S in the liver. Warfarex doesn't act on the formed clots, but prevents their growth and formation of new clots(thrombs).

Indications: Warfarex is used in prophylaxis and treatment of the diseases associated with clots formation:

Thrombosis of the deep veins
Thrombembolia of the lungs
Atrial fibrillation
Heart attack(myocordial infarction)
In prosthesis of the cardiac valves

Contraindications and cautions: Warfarin should not be used in the following conditions:

Bleeding or danger of bleeding development in some severe diseases
Bacterial endocarditis
Severe liver failure
Obstructive jaundice
Severe kidney failure
Diabetes
Disseminated intravascular coagulation
Deficiency of C and S proteins
Bleeding diathesis
Low platelet count
Stomach and duodenal ulcers in aggravation phase
Stroke
Chronic alcoholism
Severe hypertension
Recent surgical interventions
Children
Pregnancy
Known hypersensitivity to warfarin

Blood-thinners increases the risk of bleedings. During the treatment regularly control your blood coagulation system. Tell your doctor if you experienced digestive system disorders while the treatment with warfarin.

Adverse effects: There are possible side-effects associated with this medicine that can affect individuals in different ways. If a side effect is stated here, that does not necessarily mean the fact that all people using Warfarex will experience it or any other.

Blood-coagulation system: bleedings
Cardiovascular system: in rare cases disorders of the circulation in extremities and internals
Digestive system: nausea, vomiting, diarrhea, stomach pain, liver dysfunction
Allergic reactions:hives, itching, dermatitis.
Others: fever, weakness, alopecia.

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with Warfarex, please read the information provided with Warfarex or consult your doctor or pharmacist.

Interactions: It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with Warfarex. Similarly, check with your doctor or pharmacist before taking any new medication while taking this one, to ensure that the combination is safe.

Allopurinol, amiodarone, anabolic steroids ,heparin, glibenclamide, glucagon, levamisole, clarithromycin, diazoline, disulfiram, danazol, diazoxide, disopyramide, isoniaside, ketoconazole, clofibrate, metronidazole, miconazole, nalidixic acid, nilutamid, chinine, tamoxifen, thyroxin, chinine, chinidine, fluconazole, chloramphenicole, cimetidine, laxatives, dipiridamole ethanol may enhance the effects of Warfarex.

Warfarex may interact with:

Antibiotics (azithromycin, erythromycin, tetracycline, cephalosorins);
Non-steroidal anti-inflammatory agents (Acetylsalicylic acid [ASA], celecoxib); acetaminophen;
Antidepressants (fluoxetine, paroxetine, sertraline);
Stomach ulcer / acid reducing agents (cimetidine, omeprazole, ranitidine);
Lipid lowering agents (fibrates, statins such as lovastatin and simvastatin);

Diuretics, barbiturates, vitamin K, glutetimid, griseofulvin, dicloxacillin, carbamazepine, mianserin, retinoid, rifampicin, sucralfate, phenazone, colestiramin impair the effects of Warfarex. Smoking impair the effects of Warfarex.

Additional Information: DO NOT SHARE Warfarex with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.